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AGA has not been detected as a mutational cancer driver

AGA
Ensembl id ENSG00000038002
Mutated samples
Coding Sequence 26 (0.4%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AGA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 8 2.17
Lung squamous cell carcinoma No 3 3 1.72
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 1 1 0.26
Renal clear cell carcinoma No 2 1 0.24
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Thyroid carcinoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence