Top
ADRA2C has not been detected as a mutational cancer driver

ADRA2C
Ensembl id ENSG00000184160
Mutated samples
Coding Sequence 19 (0.3%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADRA2C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 3 2 0.51
Lung squamous cell carcinoma No 2 2 1.15
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Cutaneous melanoma No 3 1 0.27
Neuroblastoma No 1 1 0.48
Head and neck squamous cell carcinoma No 3 1 0.27
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence