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ADORA1 has not been detected as a mutational cancer driver

ADORA1
Ensembl id ENSG00000163485
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADORA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 6 1.63
Head and neck squamous cell carcinoma No 6 4 1.07
Lung squamous cell carcinoma No 3 3 1.72
Uterine corpus endometrioid carcinoma No 5 3 1.30
Stomach adenocarcinoma No 8 3 1.86
Lung adenocarcinoma No 6 2 0.51
Colorectal adenocarcinoma No 6 2 0.87
Prostate adenocarcinoma No 3 1 0.41
Breast carcinoma No 2 1 0.09
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 3 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence