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ADH6 has not been detected as a mutational cancer driver

ADH6
Ensembl id ENSG00000172955
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADH6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 10 2.71
Lung adenocarcinoma No 7 5 1.28
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 1 1 0.09
Uterine corpus endometrioid carcinoma No 1 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 2 1 0.27
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence