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ADAM30 has not been detected as a mutational cancer driver

ADAM30
Ensembl id ENSG00000134249
Mutated samples
Coding Sequence 77 (1.1%)
Protein Affecting 61 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADAM30 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 27 7.32
Breast carcinoma No 6 6 0.52
Glioblastoma multiforme No 4 4 1.06
Lung adenocarcinoma No 4 3 0.77
Stomach adenocarcinoma No 5 3 1.86
Small cell lung carcinoma No 4 3 4.35
Bladder carcinoma No 3 2 2.04
Lung squamous cell carcinoma No 2 2 1.15
Neuroblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 2 1 0.59
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence