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ADAM23 has not been detected as a mutational cancer driver

ADAM23
Ensembl id ENSG00000114948
Mutated samples
Coding Sequence 75 (1.1%)
Protein Affecting 62 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ADAM23 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 12 3.25
Lung adenocarcinoma No 9 9 2.30
Breast carcinoma No 9 7 0.61
Lung squamous cell carcinoma No 7 5 2.87
Bladder carcinoma No 4 4 4.08
Stomach adenocarcinoma No 4 4 2.48
Uterine corpus endometrioid carcinoma No 3 3 1.30
Small cell lung carcinoma No 3 3 4.35
Colorectal adenocarcinoma No 3 3 1.31
Prostate adenocarcinoma No 2 2 0.82
Hepatocarcinoma No 3 2 2.22
Renal clear cell carcinoma No 4 2 0.48
Esophageal carcinoma No 2 2 1.37
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence