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ACVR1 × Endometrial Carcinoma ×

ACVR1 is detected as a mutational cancer driver in Endometrial Carcinoma

ACVR1 reports in Endometrial Carcinoma (UCEC)

Cancer type details
Endometrial Carcinoma
Cohorts 4
Samples 691
Mutations 3,631,382
Driver genes 69
Gene details
ACVR1
Ensembl ID ENSG00000115170
Transcript ID ENST00000434821
Protein ID ENSP00000405004
Cohorts where is driver 1
Mutated samples 21
Mutated samples (%) 3.04
Mutations 25
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence