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ACAP2 has not been detected as a mutational cancer driver

ACAP2
Ensembl id ENSG00000114331
Mutated samples
Coding Sequence 53 (0.8%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ACAP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 8 5 1.33
Renal clear cell carcinoma No 5 4 0.96
Cutaneous melanoma No 9 4 1.08
Stomach adenocarcinoma No 3 3 1.86
Small cell lung carcinoma No 3 3 4.35
Lung adenocarcinoma No 3 2 0.51
Bladder carcinoma No 3 2 2.04
Lung squamous cell carcinoma No 4 2 1.15
Glioblastoma multiforme No 3 2 0.53
Breast carcinoma No 1 1 0.09
Pancreas adenocarcinoma No 1 1 0.47
Serous ovarian adenocarcinoma No 1 1 0.32
Hepatocarcinoma No 3 0 0.00
Thyroid carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence