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ACAA1 has not been detected as a mutational cancer driver

ACAA1
Ensembl id ENSG00000060971
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ACAA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 6 1.63
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 1 1 1.11
Lung squamous cell carcinoma No 2 1 0.57
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 2 1 0.62
Glioblastoma multiforme No 1 1 0.26
Lung adenocarcinoma No 3 0 0.00
Bladder carcinoma No 2 0 0.00
Breast carcinoma No 5 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Thyroid carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 15 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 2 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence