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ABCG5 has not been detected as a mutational cancer driver

ABCG5
Ensembl id ENSG00000138075
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ABCG5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 11 8 2.05
Cutaneous melanoma No 10 4 1.08
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 3 2 1.15
Colorectal adenocarcinoma No 3 2 0.87
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence