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ABCC5 has not been detected as a mutational cancer driver

ABCC5
Ensembl id ENSG00000114770
Mutated samples
Coding Sequence 95 (1.4%)
Protein Affecting 71 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ABCC5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 16 4.34
Lung adenocarcinoma No 14 10 2.56
Breast carcinoma No 8 6 0.52
Lung squamous cell carcinoma No 7 6 3.45
Renal clear cell carcinoma No 6 6 1.44
Stomach adenocarcinoma No 7 5 3.11
Head and neck squamous cell carcinoma No 7 5 1.33
Bladder carcinoma No 4 4 4.08
Glioblastoma multiforme No 7 4 1.06
Prostate adenocarcinoma No 2 2 0.82
Serous ovarian adenocarcinoma No 3 2 0.63
Hepatocarcinoma No 3 1 1.11
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 1 1 4.35
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence