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ESR1 × Endometrial Carcinoma ×

ESR1 is detected as a mutational cancer driver in Endometrial Carcinoma

ESR1 reports in Endometrial Carcinoma (UCEC)

Cancer type details
Endometrial Carcinoma
Cohorts 4
Samples 691
Mutations 3,631,382
Driver genes 69
Gene details
ESR1
Ensembl ID ENSG00000091831
Transcript ID ENST00000440973
Protein ID ENSP00000405330
Cohorts where is driver 1
Mutated samples 14
Mutated samples (%) 2.03
Mutations 21
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence