TP53 is detected as a mutational cancer driver in Stomach Adenocarcinoma
TP53 reports in Stomach Adenocarcinoma (STAD)
Cancer type details
Stomach Adenocarcinoma |
---|
Cohorts
6
Samples 858 Mutations 6,723,174 Driver genes 75 |
Gene details
TP53 |
---|
Ensembl ID
ENSG00000141510
Transcript ID ENST00000269305 Protein ID ENSP00000269305 |
Cohorts where is driver
6
Mutated samples 319 Mutated samples (%) 37.18 Mutations 396 |
Mode of action Loss of function |
Known driver True |
Method signals per Cohort
Cohort | Methods | Samples | Samples (%) |
---|
In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
STAD (Stomach Adenocarcinoma) | 3528 | 630 | 17.86 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence | Driver | Driver score |
---|