CDKN2A is detected as a mutational cancer driver in Lung Squamous Cell Carcinoma
CDKN2A reports in Lung Squamous Cell Carcinoma (LUSC)
Cancer type details
Lung Squamous Cell Carcinoma |
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Cohorts
6
Samples 703 Mutations 4,282,647 Driver genes 75 |
Gene details
CDKN2A |
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Ensembl ID
ENSG00000147889
Transcript ID ENST00000498124 Protein ID ENSP00000418915 |
Cohorts where is driver
4
Mutated samples 81 Mutated samples (%) 11.52 Mutations 96 |
Mode of action Loss of function |
Known driver True |
Method signals per Cohort
Cohort | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
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LUSC (Lung Squamous Cell Carcinoma) | 1494 | 270 | 18.07 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence | Driver | Driver score |
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