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PBRM1 × Stomach Adenocarcinoma ×

PBRM1 is detected as a mutational cancer driver in Stomach Adenocarcinoma

PBRM1 reports in Stomach Adenocarcinoma (STAD)

Cancer type details
Stomach Adenocarcinoma
Cohorts 6
Samples 858
Mutations 6,723,174
Driver genes 75
Gene details
PBRM1
Ensembl ID ENSG00000163939
Transcript ID ENST00000409057
Protein ID ENSP00000386593
Cohorts where is driver 1
Mutated samples 12
Mutated samples (%) 1.40
Mutations 24
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence